Journal Articles

Below you will find a list of publications from the Biomaterials and Nanomedicine lab. Each listing includes a link to the Journal database if available. 

* Indicate students in Liu Lab


60. Cipriano AF*, Sallee A*, Tayoba M*, Cortez Alcaraz MC*, Lin A*, Guan RG, Zhao ZY*, Tayoba M*, Sanchez J*, and Liu H. Cytocompatibility and Early Inflammatory Response of Human Endothelial Cells in Direct Culture with Mg-Zn-Sr Alloys. Acta Biomaterialia. 16: 30547-5, 2016. Epub ahead of print 10/13/2016. DOI: 10.1016/j.actbio.2016.10.020. (PMID: 27746360)

59. Tian Q*, Rivera-Castaneda L*, Liu H. Optimization of nano-hydroxyapatite/poly(lactic-co-glycolic acid) coatings on magnesium substrates using one-step electrophoretic depositionMaterials Letters. 2016. Available online 19 September 2016. DOI: 10.1016/j.matlet.2016.09.072.

58. Tian Q*, Deo M*, Rivera-Castaneda L*, Liu H. Cytocompatibility of Magnesium Alloys with Human Urothelial Cells: A Comparison of Three Culture Methodologies. ACS Biomaterials Science and Engineering. 2016. DOI: 10.1021/acsbiomaterials.6b00325.

57. Su N, Guan R, Wang X, Wang Y, Jiang W*, Liu H. Grain Refinement in an Al-Er Alloy during Accumulative Continuous Extrusion Forming. Journal of Alloys and Compounds. 680: 283-290, 2016.

56. Johnson I*, Wang SM*, Silken C*, Liu H. A systemic study on key parameters affecting nanocomposite coatings on magnesium substrates. Acta Biomaterialia. 2016 Mar 19. pii: S1742-7061(16)30120-9. doi: 10.1016/j.actbio.2016.03.026. [PMID: 27006335]

54. Tie D, Guan R, Liu H, Cipriano A*, Liu Y, Wang Q, Huang Y, Hort N. An In Vivo Study on the Metabolism and Osteogenic Activity of Bioabsorbable Mg-1Sr Alloy. Acta Biomaterialia. 2016 Jan 1;29:455-467. doi: 10.1016/j.actbio.2015.11.014. Epub 2015 Nov 11. (PMID: 26577986)


53. Wang P, Xia M, Liang O, Sun K, Cipriano AF*, Schroeder T, Liu H, Xie YH. Label-free SERS Selective Detection of Dopamine and Serotonin Using Graphene-Au Nanopyramid Heterostructure. Analytical Chemistry. 87(20): 10255-10261. 2015. Epub ahead of print, Sep 18, 2015. DOI: 10.1021/acs.analchem.5b01560. (PMID: 26382549)

52. Zhang N*, Lock J*, Sallee A*, and Liu H. Magnetic Nanocomposite Hydrogel for Potential Cartilage Tissue Engineering: Synthesis, Characterization, and Cytocompatibility with Bone Marrow Derived Mesenchymal Stem Cells. ACS Applied Materials and Interfaces. Accepted 08/28/2015. DOI: 10.1021/acsami.5b06939. (PMID: 26360342)

51. Zhao ZY, Guan RG, Guan XH, Zhang J, Sun XP, Liu H. Effects of Electromagnetic Stirring, Shearing, and Extrusion on TiB2 and TiAl3 Particles in Al-5Ti-1B (wt.%) Alloy. Materials and Manufacturing Processes. 0: 1-6, 2015. DOI: 10.1080/10426914.2015.1019109.

50. Iskandar ME, Aslani A, Tian Q*, and Liu H. Nanostructured calcium phosphate coatings on magnesium alloys: characterization and cytocompatibility with mesenchymal stem cells. Journal of Materials Science: Materials in Medicine 26(5): 1-18, 2015. DOI:

49. Tian Q*, and Liu H. Electrophoretic Deposition and Characterization of Nanocomposites and Nanoparticles on Magnesium Substrates. Nanotechnology. 26(17): 175102, 2015. DOI:10.1088/0957-4484/26/17/175102

48. Nguyen TY*, Cipriano AF*, Guan R, Zhao Z, and Liu H. In Vitro Interactions of Blood, Platelet, and Fibroblast with Biodegradable Magnesium-Zinc-Strontium Alloys. Journal of Biomedical Materials Research Part A. Accepted 02/17/2015. Epub ahead of print. DOI: 10.1002/jbm.a.35429. (PMID: 25690931)


47. Cipriano AF*, Sallee A*, Guan RG, Zhao ZY, Tayoba M*, Sanchez J*, Liu H. Investigation on Magnesium-Zinc-Calcium Alloys and Bone Marrow Derived Mesenchymal Stem Cell Responses in Direct Culture. Acta Biomaterialia. 12(1): 298-321, 2015. Online First, 10/15/2014. DOI: 10.1016/j.actbio.2014.10.018.

46. Mai ED*, and Liu H. Investigation on Magnesium Degradation under Flow versus Static Conditions using a Novel Impedance-Driven Flow Apparatus. Progress in Natural Science: Materials International. 24: 554-560, 2014. Online 10/28/2014. DOI: 10.1016/j.pnsc.2014.08.012.

45. Tian Q*, and Liu H. Electrophoretic Deposition and Characterization of Biocomposites on Magnesium for Orthopedic Applications. Advanced Materials Research. 922: 761-766, 2014.

44. Nguyen TY*, Guan R, Cipriano AF*, Zhao Z, and Liu H. Characterization of Magnesium Alloy Degradation in Whole Blood and Platelet Rich Plasma. Advanced Materials Research. 922: 543-548, 2014.

43. Miller C*, Cipriano AF*, and Liu H. Surface Characterization of Magnesium Anodized in a 10M KOH Electrolyte. Advanced Materials Research. 922: 513-518, 2014.

42. Johnson I*, Islam MS, Park BH, and Liu H. Investigation of Biodegradable Composite Coated Magnesium Alloy Using Optical Coherence Tomography. Advanced Materials Research. 922: 292-297, 2014.

41. Cipriano AF*, Miller C*, and Liu H. Cytocompatibility of Magnesium-Zinc-Calcium Alloys with Bone Marrow Derived Mesenchymal Stem Cells. Advanced Materials Research. 922: 1-6, 2014.

40. Lock JY*, Tu J*, and Liu H. Degradation of Magnesium Alloys in Artificial Urine Solution for Urological Applications. Materials Science Forum. 783-786: 413-418, 2014.

39. Cipriano AF*, Miller C*, and Liu H. Anodic Growth and Biomedical Applications of TiO2 Nanotubes. Journal of Biomedical Nanotechnology. 10(10): 2977-3003, 2014.

38. Sebaa M*, Nguyen TY*, Dhillon S*, Garcia S*, and Liu H. The Effects of Poly(3, 4-ethylenedioxythiophene) (PEDOT) Coating on Magnesium Degradation and Cytocompatibility with Human Embryonic Stem Cells for Potential Neural Applications. Journal of Biomedical Materials Research Part A. Online First, 3/5/2014. DOI: 10.1002/jbm.a.35142. (PMID: 24677580)


37. Jiang W*, Johnson I*, and Liu H. Nanostructured Coatings Improve Properties of Biodegradable Metals for Medical Implants. SurFACTS in Biomaterials. 8(4): 10-13, 2013. (Invited)

36. Nguyen TY*, Liew CG, Liu H. An In Vitro Mechanism Study on the Proliferation and Pluripotency of Human Embryonic Stems Cells in Response to Magnesium Degradation. PLoS ONE 8(10): e76547. doi:10.1371/journal.pone.0076547. 10/17/2013.

35. Cipriano AF*, De Howitt N*, Gott SC, Miller C*, Rao MP, Liu H. Bone Marrow Stromal Cell Adhesion and Morphology on Micro- and Sub-micropatterned Titanium. Journal of Biomedical Nanotechnology. 10(4): 660-668(9), 2014. Accepted 7/8/2013.

34. Johnson I*, Akari K*, Liu H. Nanostructured Hydroxyapatite/Poly(lactic-co-glycolic acid) (PLGA) Composite Coating for Controlling Magnesium Degradation in Simulated Body Fluid. Nanotechnology. 24(37): 375103, Epub 08/23/2013. DOI: 10.1088/0957-4484/24/37/375103. (PMID: 23975041)

33. Lock JY*, Wyatt E*, Upadhyayula S, Whall A*, Nunez V, Vullev VI, Liu H. Degradation and Antibacterial Properties of Magnesium Alloys in Artificial Urine for Potential Resorbable Ureteral Stent Applications. Journal of Biomedical Materials Research Part A. DOI: 10.1002/jbm.a.34741. Online First, 4/2/2013. (PMID: 23564415)

32. Johnson I*, Liu H. A Study on Factors Affecting the Degradation of Magnesium and A Magnesium-Yttrium Alloy for Biomedical Applications. PLOS ONE 8(6): e65603. DOI: 10.1371/journal.pone.0065603. 6/14/2013. (PMID: 23799028)

31. Guan R, Cipriano AF*, Zhao Z, Lock JY*, Tie D, Zhao T, Cui T, Liu H. Development and Evaluation of a Magnesium-Zinc-Strontium Alloy for Biomedical Applications - Alloy Processing, Microstructure, Mechanical Properties, and Biodegradation. Materials Science and Engineering: C. 33(7): 3661-3669, 2013. DOI: 10.1016/j.msec.2013.04.054. Online First, 5/3/2013.

30. Nguyen TY*, Liu H. A Review of Current Advances in Biomaterials for Neural Tissue Regeneration. Recent Patents on Biomedical Engineering. 6: 29-39, 2013.

29. Iskandar ME*, Aslani A, Liu H. The Effects of Nanostructured Hydroxyapatite Coating on the Biodegradation and Cytocompatibility of Magnesium Implants. Journal of Biomedical Materials Research Part A. 101A(8): 2340-2354, 2013. DOI: 10.1002/jbm.a.34530, Epub ahead of print, 1/28/2013. (PMID: 23359521)

28. Cipriano AF*, Zhao T, Johnson I*, Guan R, Garcia S*, Liu H. In vitro Degradation of Four Magnesium-Zinc-Strontium Alloys and Their Cytocompatibility with Human Embryonic Stem Cells. Journal of Materials Science: Materials in Medicine. 24(4): 989-1003, 2013. DOI 10.1007/s10856-013-4853-1, Online First, 1/30/2013. (PMID: 23361966)

27. Sebaa M*, Dhillon S*, Liu H. Electrochemical Deposition and Evaluation of Electrically Conductive Polymer Coating on Biodegradable Magnesium Implants for Neural Applications. Journal of Materials Science: Materials in Medicine. 24(2): 307-316, 2013. DOI: 10.1007/s10856-012-4796-y, Online First, 10/27/2012. (PMID: 23104085)

26. Sebaa M*, Nguyen TY*, Paul RK, Mulchandani A, Liu H. Graphene and Carbon Nanotube-Graphene Hybrid Nanomaterials for Human Embryonic Stem Cell Culture. Materials Letters. 92: 122-125, 2013. DOI: 10.1016/j.matlet.2012.10.035, 11/12/2012 online first.


25. Li JY, Liu H, and Huang PW. Effects of Pre-precipitation of Cr2N on Microstructures and Properties of High Nitrogen Stainless Steel. Journal of Central South University of Technology. 19(5): 1189-1195, 2012. DOI: 10.1007/s11771-012-1127-x

24. Lock JY*, Nguyen TY*, Liu H. Nanophase Hydroxyapatite and Poly(lactide-co-glycolide) Composites Promote Human Mesenchymal Stem Cell Adhesion and Osteogenic Differentiation In Vitro. Journal of Materials Science: Materials in Medicine. 23(10): 2543-2552, 2012. DOI: 10.1007/s10856-012-4709-0, July 9th, 2012 online first. (PMID: 22772475)

23. Lock JY*, Liu H. Nanotechnology Enabled Drug Delivery Systems for Bone and Cartilage Regeneration. Recent Patents on Biomedical Engineering. 5: 51-56, 2012.

22. Johnson I*, Liu H. In vitro Evaluation of Magnesium-based Metallic Biomaterials and the Need for Standardization. Biomaterials Forum. 34(4): 9-14, 2012. 

21. Guan R, Johnson I*, Cui T, Zhao T, Zhao Z, Li X, and Liu H. Electrodeposition of Hydroxyapatite Coating on Mg-4.0Zn-1.0Ca-0.6Zr Alloy and In Vitro Evaluation of Degradation, Hemolysis and Cytotoxicity. Journal of Biomedical Materials Research Part A. 100A(4): 999-1015, 2012. (PMID: 22307984)

20. Johnson I*, Perchy D*, Liu H. In vitro Evaluation of the Surface Effects on Magnesium-Yttrium Alloy Degradation and Mesenchymal Stem Cell Adhesion. Journal of Biomedical Materials Research Part A. 100A(2): 477-485, 2012. Available online (DOI: 10.1002/jbm.a.33290) 29 November 2011. (PMID: 22125092)


19. Lock JY*, Liu H.  Nanomaterials Enhanced Osteogenic Differentiation of Human Mesenchymal Stem Cells Similar to a Short Peptide of BMP-7. International Journal of Nanomedicine. 6: 2769-2777. 2011. (PMID: 22114505)
18. Liu HThe Effects of Surface and Biomolecules on Magnesium Degradation and Mesenchymal Stem Cell Adhesion. Journal of Biomedical Materials Research Part A. 99A(2): 249-260, 2011. Available online 16 August 2011. (PMID: 21976450)

17. Liu H and Webster TJ. Enhanced Biological and Mechanical Properties of Well-Dispersed Nanophase Ceramics in Polymer Composites: From 2D to 3D Printed Structures. Materials Science and Engineering: C. 31(2): 77-89, 2011. Available online 3 August 2010.


16. Liu H and Webster TJ. Mechanical Properties of Dispersed Ceramic Nanoparticles in Polymer Composites for Orthopedic Applications. International Journal of Nanomedicine. 5: 299-313, 2010.
(PMID: 20463945)

15. Liu H and Webster TJ. Ceramic/Polymer Nanocomposites with Tunable Drug Delivery Capability at Specific Disease Sites. Journal of Biomedical Materials Research. 93(3): 1180-1192, 2010. Epub ahead of print, Sep 23, 2009. (PMID: 19777574)


14. Liu H, Jiang W and Malshe A. Novel Nanostructured Hydroxyapatite Coating for Dental and Orthopedic Implants.
JOM. 61(9): 67-69, 2009. September 2009.

13. Ergun C, Liu H and Webster TJ. Osteoblast Adhesion on Novel Machinable Calcium Phosphate/Lanthanum Phosphate Composites for Orthopedic Applications. Journal of Biomedical Materials Research Part A. 89(3): 727-733, 2009. Epub ahead of print, May 7, 2008. (PMID: 18464257)


Liu H, Yazici H, Ergun C and Webster TJ. An In Vitro Evaluation of the Ca/P Ratio Factor in Cytocompatibility of Nano-to-Micron Particulate Calcium Phosphates for Bone Regeneration.  Acta Biomaterialia. 4(5): 1472-1479, 2008.
(PMID: 18394980)
* Rated as ScienceDirect Top 25 Hottest Articles; Acta Annual Award Paper

11. Ergun C, Liu H, Webster TJ, Olcay E, Yilmaz S and Sahin FC. Increased Osteoblast Adhesion on Nanoparticulate Calcium Phosphates with Higher Ca/P Ratios. Journal of Biomedical Materials Research A. 85(1): 236-241, 2008. (PMID: 17688268)


10. Ergun C, Liu H, Halloran JW and Webster TJ. 
Increased Osteoblast Adhesion on Nanograined Hydroxyapatite and Tricalcium Phosphate Containing Calcium Titanate. Journal of Biomedical Materials Research. 80A(4): 990-997, 2007.
(PMID: 17120201)

9. Liu H and Webster TJ. The Promise of Aerosol Printed 3D Nanostructured Ceramic/Polymer Composites as Next Generation Orthopedic Tissue Engineering Scaffolds. Materials and Processes for Medical Devices. July 2007; Featured at

8. Liu H and Webster TJ. Nanomedicine for Implants: A Review of Studies and Necessary Experimental Tools. Biomaterials. 28(2): 354-369, 2007. (PMID: 17049982)
*Rated as ScienceDirect Top 25 Hottest Articles


7. Liu H, Slamovich EB and Webster TJ. Increased Osteoblast Functions among Nanophase Titania/Poly(lactide-co-glycolide) Composites of the Highest Nanometer Surface Roughness.  Journal of Biomedical Materials Research. 78A(4): 798-807, 2006.
(PMID: 16741979)

6. Liu H, Slamovich EB and Webster TJ. Less Harmful Acidic Degradation of Poly(lactic-co-glycolic acid) Bone Tissue Engineering Scaffolds Through Titania Nanoparticle Addition.  International Journal of Nanomedicine. 1(4): 541 545, 2006. (PMID: 17722285)


5. Palin E, Liu H, and Webster TJ. Mimicking the Nanofeatures of Bone Increases Bone-forming Cell Adhesion and Proliferation. Nanotechnology. 16(9): 1828-1835, 2005.

4. Liu H, Slamovich EB and Webster TJ. Increased Osteoblast Functions on Nanophase Titania Dispersed in Poly-lactic-co-glycolic Acid Composites. Nanotechnology. 16(7):S601-608, 2005.

3. Liu H, Slamovich EB and Webster TJ. Increased Osteoblast Functions on Poly-lactic-co-glycolic-acid with Highly Dispersed Nanophase Titania. Journal of Biomedical Nanotechnology. 1(1): 83-89, 2005.


2. Liu H and Xie J. Database System for Design of Extrusion Dies. Journal of University of Science and Technology Beijing/Beijing Ke Ji Da Xue Xue Bao. 23(1): 63-72, 2001.

1. Chen J, Xie J and Liu H. Extrusion Characteristics of Composite Powders of Stainless Steel and Zirconia.  Journal of University of Science and Technology Beijing/Beijing Ke Ji Da Xue Xue Bao. 19(6): 590-598, 1997.